解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Thyronine (T4), triiodothyronine (T3), and reverse-triiodothyronine (rT3) levels were evaluated in cerebrospinal fluid (CSF) and in serum of 12 patients with definite amyotrophic lateral sclerosis (ALS) by specific radioimmunoassays. Circulating microsomal and thyroglobulin antibodies were also evaluated. In all patie...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314221
更新日期:1989-01-01 00:00:00
abstract::There is still a need to prove that even static magnetic fields up to 1.5 T used in magnetic resonance imaging (MRI) are biologically safe and harmless for humans. Recordings of median and ulnar nerves and brain-stem auditory evoked potentials in 20 patients were completed prior to and after MRI investigation of the c...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314248
更新日期:1988-11-01 00:00:00
abstract::A 73-year-old woman presented with multifocal cerebral dysfunction of 1 month's duration. Cranial CT scanning revealed unusual widespread abnormalities. Brain biopsy showed amyloid angiopathy affecting vessels in the meninges and cerebral cortex, with associated granulomatous angiitis. There was no clinical evidence o...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314491
更新日期:1988-09-01 00:00:00
abstract::Eight cases of malignancies with concurrent motor neuron disease (MND), derived from an unselected population representing all cases of MND diagnosed during a 15-year period in two Italian provinces, were studied to verify the existence of paraneoplastic forms of the disease. No statistically significant association b...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314238
更新日期:1988-07-01 00:00:00
abstract::In 40 rabbits cerebral ischaemia was induced by autologous blood clot emboli injected into the middle cerebral artery. Autologous blood clot formed spontaneously (within 2 h) in a catheter fixed in the internal carotid artery. The effects of embolization were investigated on arterial blood pressure, respiration, local...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314181
更新日期:1988-05-01 00:00:00
abstract::Intrathecal synthesis of immunoglobulin G (IgG) specific to Treponema pallidum, ssp. pallidum, or to the human immunodeficiency virus 1 (HIV-1) was investigated in patients with contemporary treponemal and HIV-1 infections. Using a T. pallidum and an HIV-1 IgG enzyme-linked immunosorbent assay, specific antibody units...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314359
更新日期:1988-03-01 00:00:00
abstract::The bulbocavernosus reflex (BCR) was examined in 39 normal potent men and in 252 patients with impaired potency of varying aetiology. For BCR evaluation minimum, maximum and mean latencies, the temporal dispersion in ten successive responses, together with minimum and maximum side differences from simultaneous recordi...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314350
更新日期:1988-03-01 00:00:00
abstract::The similar localization of intracranial calcification in hypoparathyroidism and in Fahr disease without parathyroid gland disorder suggests that in these two disorders the pathomechanism of calcium phosphate deposition in the brain may be similar. It may be that in Fahr disease some factors, such as chronic respirato...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314315
更新日期:1988-01-01 00:00:00
abstract::A 57-year-old male was repeatedly admitted to hospital because of complex neurological symptoms, including radicular pain, disturbance of micturition, seizures, and severely impaired mental state. The diagnosis was encephalomyeloradiculitis possibly of viral origin, and treatment with immunosuppressants was initiated....
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314303
更新日期:1988-01-01 00:00:00
abstract::In a fatal case of neuroleptic malignant syndrome, a muscle sample taken within 1 h of death showed acute myopathic features with absence of muscle glycogen and neutral lipid. These features suggest that hyperpyrexia in this syndrome may be caused by heat production from uncoupled phosphorylation in muscle and imply t...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00718024
更新日期:1987-12-01 00:00:00
abstract::The clinical features of 31 cases of syringomyelic syndrome, confirmed by metrizamide CT myelography (CTM) or magnetic resonance imaging (MRI), were analysed. Bilateral suspended sensory disturbance, previously regarded as a characteristic feature, was encountered in only 2 cases (6.5%). Thirteen patients (41.9%) show...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314193
更新日期:1987-10-01 00:00:00
abstract::Cerebral amyloid angiopathy (CAA) was found in 57% of 123 autopsy brains removed from patients aged 59-101 years. The incidence of CAA increased with age. CAA was seen most frequently in the occipital cortex. Immunohistochemically, amyloid of CAA was positive for amyloid P component and negative for human AA protein a...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314080
更新日期:1987-08-01 00:00:00
abstract::A girl with rapid-onset, bulbospinal muscular atrophy and deafness is described. The patient's mother and brother showed EMG features consistent with subclinical involvement. T is bulbospinal form of spinal muscular atrophy associated with deafness described by Vialetto and van Laere closely resembles the Madras type ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314095
更新日期:1987-08-01 00:00:00
abstract::Neurological complications in the acquired immunodeficiency syndrome (AIDS) are an important aspect of this new infectious disease and occur frequently. The existence of neurotropic variants of the human immunodeficiency virus (HIV), the causative agent of AIDS, is probable. Direct infection of the nervous system with...
journal_title:Journal of neurology
pub_type: 杂志文章,评审
doi:10.1007/BF00314279
更新日期:1987-06-01 00:00:00
abstract::An IgM antibody cytotoxic to normal human lymphocytes was found in 46.2% (male: 61.5%; female: 30.8%) of sera from chronic schizophrenics by means of a complement-dependent cytotoxicity test. The relationship between this antibody and the immunological manifestations of schizophrenia is discussed. ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314296
更新日期:1987-06-01 00:00:00
abstract::To investigate the role of endogenous opioid peptides in the pathophysiology of cerebral ischaemia, the CSF levels of immunoreactive beta-endorphin and leu-enkephalin in 16 patients with cerebral infarction were measured. Both the CSF beta-endorphin and leu-enkephalin levels in the acute stage of cerebral infarction w...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314282
更新日期:1987-06-01 00:00:00
abstract::Cobrotoxin-binding protein was isolated by affinity chromatography from human thymoma which had been surgically removed from patients with myasthenia gravis. The protein was composed of polypeptides with a molecular mass of 40, 51, 65, and 74 kilodaltons as determined by polyacrylamide gel electrophoresis in the prese...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00618251
更新日期:1987-05-01 00:00:00
abstract::An ultrastructural study of biopsied muscles was performed in seven patients with rimmed vacuolar distal myopathy, which was characterized by prominent rimmed vacuoles in the muscle fibers. The earliest changes noted were focal proliferation of the Golgi's apparatus and mitochondrial degeneration with myofibrillar los...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314132
更新日期:1987-04-01 00:00:00
abstract::The cases of identical twins with ataxia telangiectasia, early intellectual impairment and progressive spasticity are reported. Immunological tests revealed reduced levels of serum and salivary IgA, increased B cells, reduced T cells and raised alpha-fetoprotein. CT scan performed in one of the twins was normal. The p...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314163
更新日期:1986-10-01 00:00:00
abstract::Three patients developed acute Guillain-Barré syndrome while on steroid treatment. The first patient suffered from ulcerative colitis and developed Guillain-Barré syndrome when the steroid dosage was being tapered. Another patient with long-standing multiple sclerosis received steroids during relapse and the Guillain-...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314023
更新日期:1986-08-01 00:00:00
abstract::Clinical data and the serum and cerebrospinal fluid (CSF) findings of 71 patients with Guillain-Barré syndrome (GBS), 7 with Fisher syndrome and 24 with chronic inflammatory polyradiculoneuropathy (CIP), were analysed. Isoelectric focusing of serum and CSF together with different formulae and diagrams were applied to ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314019
更新日期:1986-08-01 00:00:00
abstract::A 15-year-old boy with Tourette's syndrome exhibited severe involuntary self-mutilatory behavior. While clonidine effectively controlled the motor and phonic tics, it failed to ameliorate the self-mutilatory behavior. Administration of oxycodone (50 mg/day) combined with clonidine produced a dramatic reduction in the ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314429
更新日期:1986-06-01 00:00:00
abstract::The diagnosis and management of lesions of the brachial roots and of the brachial plexus is improved by appropriate investigation, both in acute and chronic disorders. The choice of investigation should be determined by the clinical problem. Since they are relatively non-invasive, electrophysiological investigations a...
journal_title:Journal of neurology
pub_type: 杂志文章,评审
doi:10.1007/BF00314416
更新日期:1986-06-01 00:00:00
abstract::Brains from 54 patients with organic dementia were examined systematically. As in previous investigations a predominance of Alzheimer type changes was observed. Seventeen patients showed Lewy bodies in the nucleus basalis, the substantia nigra and the locus coeruleus as well as other lesions of parkinsonian type. In 5...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313858
更新日期:1986-04-01 00:00:00
abstract::The computed tomography, magnetic resonance imaging and angiographic findings are described in a patient with Klippel-Trenaunay syndrome, who also had a cerebral haemorrhage from an arteriovenous malformation. The resulting aphasia disappeared completely after resorption of the haemorrhage. In this syndrome, the occur...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313992
更新日期:1986-02-01 00:00:00
abstract::Three cases of Fahr's syndrome are described. All patients had disturbances of calcium metabolism and had had a meningoencephalitis in childhood. It is suggested that gliovascular changes, induced by cerebral inflammation, can later facilitate the occurrence of calcification of the striopallidodentate system when abno...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313985
更新日期:1986-02-01 00:00:00
abstract::Two patients with chorea and polycythaemia vera are described. The literature on this rare association is reviewed and its pathophysiology discussed. ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313895
更新日期:1985-01-01 00:00:00
abstract::The carotid bifurcations and the common carotid arteries of 36 patients with the diagnosis hyperactive carotid sinus syndrome (HCSS) were investigated by continuous wave (CW) Doppler ultrasonography and high-resolution real-time B-scan. Using these non-invasive tests, the functional impact of luminal stenosis and the ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313874
更新日期:1985-01-01 00:00:00
abstract::Two cases of Addison's disease associated with myasthenia gravis are reported. This association has been described only rarely in the literature. In the first case, there were marked immunological abnormalities. It is most likely that the origin of the adrenocortical insufficiency in the second case is tuberculous. Th...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313835
更新日期:1985-01-01 00:00:00
abstract::Two siblings with multiple intracranial haemangiomatosis are reported, each having psychomotor retardation, epilepsy and gyriform type calcification in the occipital and frontal lobes. There were haemangiomas in one autopsy case with calcification in the deep layers of the cortex and subcortical white matter. ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313911
更新日期:1985-01-01 00:00:00
abstract::We report a very rare case of Schwartz-Jampel syndrome associated with von Willebrand's disease. This association might be coincidental because of the different modes of inheritance of the two disorders. However, we speculate that there might be some link between the two disorders, for example in the locus of the affe...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314041
更新日期:1985-01-01 00:00:00
abstract::Multi-modality evoked potentials and computed cranial tomography (CT) were performed in ten patients with Wilson's disease to determine if any of these studies would correlate reliably with neurologic status. While all four patients with CT abnormality had neurologic signs, two additional patients with neurologic find...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314035
更新日期:1985-01-01 00:00:00
abstract::Six patients with amyotrophic lateral sclerosis were given from 800 to 4000 micrograms of thyrotropin-releasing hormone (TRH) intrathecally for a period of 2-6 months. The progressive course of this disease, manifested by increasing atrophy, paralysis and disability score, was not altered. This supports the hypothesis...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00314033
更新日期:1985-01-01 00:00:00
abstract::Clinical and neuropathological data of a 50-year-old woman with an unusual multisystem degeneration are presented. Clinically the illness was characterized by progressive ataxia with ophthalmoplegia and multiple cranial nerve palsies. Neuropathological investigation showed a severe and selective degeneration of the de...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313709
更新日期:1985-01-01 00:00:00
abstract::A case of CT-diagnosed brain-stem haematoma associated with signs of dorsal medullary involvement is reported. The patient recovered completely within 1 month. ...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313834
更新日期:1985-01-01 00:00:00
abstract::In all the sera of four patients with meningoradiculitis of Bannwarth admitted to the neurological department of the University Clinic Grosshadern in Munich in 1983, we found antibodies against Ixodes dammini spirochetes. In three patients antibodies were also present in the CSF. In one patient, we isolated spirochete...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313682
更新日期:1984-01-01 00:00:00
abstract::A recently developed technique is used to study the permeation of water through membranes of human erythrocyte ghosts. The method, based on the difference of the indices of refraction of H2O and D2O, is briefly described. Comparative measurements on erythrocyte ghosts from normal donors and from patients with Huntingt...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313655
更新日期:1984-01-01 00:00:00
abstract::The Richards-Rundle syndrome (RRS) is characterized by hearing loss, mental deterioration, ataxia, primary hypogonadism and autosomal recessive transmission. In a sibship of six members we found two sisters with RRS together with baldness, impaired GH and PRL secretion after stimulation and different degrees of impair...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313645
更新日期:1984-01-01 00:00:00
abstract::Muscle samples obtained in patients with different neuromuscular diseases were stored at 0 degree C for periods of 6-12h and were subsequently frozen for histochemical processing. Compared to reference samples which had been immediately frozen, the individual test sections displayed different degrees of swelling of th...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313934
更新日期:1984-01-01 00:00:00
abstract::Inborn errors of metabolism in 40 children have been investigated by computed tomography to obtain data on the degree of cerebral involvement in neurodegenerative and storage disorders: 20 children had various mucopolysaccharidoses, 8 sphingolipidoses , 3 mucolipidoses, 2 oligosaccharidoses , 3 ceroidlipofuscinoses an...
journal_title:Journal of neurology
pub_type: 杂志文章
doi:10.1007/BF00313718
更新日期:1984-01-01 00:00:00